Author

Justyna Mleczko

Icahn School of Medicine at Mount Sinai

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Neuroscience· 2

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Research Focus:gene regulatory network inference· 2 Organism:mouse· 2 Assay:ATAC-seq· 1 Research Focus:cell type annotation· 1 Research Focus:database / resource· 1

Frequent Co-Authors

Michelle E. EhrlichiD· 2 shared Ali Moussavi NikiD· 1 shared Azadeh Reyahi· 1 shared Bin ZhangiD· 1 shared Carlos Galicia AguirreiD· 1 shared Chuhyon CorwiniD· 1 shared Houda BenlhabibiD· 1 shared Jaroslav M. BendliD· 1 shared

Activity by Year

2020-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersNeuroscience

Michelle E. EhrlichORCID

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2 papers

Recent·Most cited

Transcriptional and epigenetic characterization of early striosomes identifies Foxf2 and Olig2 as factors required for development of striatal compartmentation and neuronal phenotypic differentiation

Maria‐Daniela Cirnaru, Sicheng Song, Kizito‐Tshitoko Tshilenge, Chuhyon Corwin, Justyna Mleczko, Carlos Galicia Aguirre, Houda Benlhabib, Jaroslav M. Bendl, Pasha Apontes, John F. Fullard, Jordi Creus‐Muncunill, Azadeh Reyahi, Ali Moussavi Nik, Peter Carlsson, Panos Roussos, , Michelle E. Ehrlich

The paper identifies Foxf2 and Olig2 as key transcription factors regulating striatal compartmentation and neuronal differentiation through RNA- and ATAC-seq analysis of murine striosomes and matrix.

eLife · Oct 5, 2021Peer-reviewedNeuroscience

Reactive or transgenic increase in microglial TYROBP reveals a TREM2-independent TYROBP-APOE link in wild-type and Alzheimer's-related mice

Mickaël Audrain, Jean‐Vianney Haure‐Mirande, Justyna Mleczko, Minghui Wang, Jennifer K. Griffin, Peter St George‐Hyslop, Paul E. Fraser, Bin Zhang, Sam Gandy, Michelle E. Ehrlich

This study shows that TYROBP-APOE signaling in microglia can occur without TREM2 and influences AD pathology in mouse models.

Alzheimer s & Dementia · Dec 12, 2020Peer-reviewedNeuroscience