Author

K. A. Bernstein

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Assay:proteomics· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:differential expression· 1 Assay:DNA methylation· 1

Frequent Co-Authors

A. De Cian· 1 shared B. Van Houten· 1 shared C. Giovannangeli· 1 shared C. Smith· 1 shared E. B. Garcin· 1 shared G. J. Brunette· 1 shared H. L. Rein· 1 shared J. Martino· 1 shared

Activity by Year

2019-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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1 shared paperCell Biology

A. De Cian

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Author profile →

2 papers

Recent·Most cited

The human Shu complex promotes RAD51 activity by modulating RPA dynamics on ssDNA.

S. R. Hengel, K. Oppenheimer, C. Smith, M. Schaich, H. L. Rein, J. Martino, K. Darrah, O. C. Ezekwenna, K. R. Burton, B. Van Houten, M. Spies, K. A. Bernstein

This study shows the Shu complex enhances RAD51 activity by stabilizing filaments and promoting RPA diffusion on ssDNA, with implications for cancer therapy.

bioRxiv · Feb 14, 2024Biochemistry

Differential Requirements for the RAD51 Paralogs in Genome Repair and Maintenance in Human Cells

E. B. Garcin, S. Gon, R. Prakash, M. R. Sullivan, G. J. Brunette, A. De Cian, J.-P. Concordet, C. Giovannangeli, W. G. Dirks, S. Eberth, K. A. Bernstein, M. Jasin, M. Modesti

This study investigates the roles of RAD51 paralogs in DNA repair across different human cell types, finding essential differences in their functions and identifying potential implications for cancer therapy.

bioRxiv · Apr 15, 2019Cell Biology