Author

K. A. Kirby

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Organism:human· 2 Approach:experimental assay· 1 Assay:proteomics· 1 Approach:statistical model· 1

Frequent Co-Authors

H. Zhang· 2 shared S. G. Sarafianos· 2 shared A. Emanuelli· 1 shared E. A. Boggs· 1 shared H. Du· 1 shared I. Melcak· 1 shared J. Fahim· 1 shared M. E. Cilento· 1 shared

Activity by Year

2021-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersBiochemistry

H. Zhang

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Author profile →

2 papers

Recent·Most cited

TSAR, Thermal Shift Analysis in R, identifies endogenous molecules that interact with HIV-1 capsid hexamers

W. M. McFadden, X. Gao, Z. Ye, X. Wen, Z. C. Lorson, H. Zhang, J. Fahim, A. Emanuelli, K. A. Kirby, S. G. Sarafianos

TSAR streamlines thermal shift assay analysis, identifying gallic acid and other metabolites that interact with HIV-1 capsid hexamers and may inhibit HIV-1 replication.

bioRxiv · Nov 29, 2023 · PreprintBiochemistry

Subgenomic SARS-CoV-2 replicon and reporter replicon cell lines enable ultrahigh throughput antiviral screening and mechanistic studies with antivirals, viral mutations or host factors that affect COVID-19 replication

S. Lan, P. R. Tedbury, Y. T. Ong, R. Shah, R. L. Slack, M. E. Cilento, H. Zhang, H. Du, N. Lulkin, U. Q. Le, K. A. Kirby, I. Melcak, W. A. Cantara, E. A. Boggs, S. G. Sarafianos

This paper develops SARS-CoV-2 replicon systems and cell lines for antiviral screening and mechanistic studies, enabling research at lower biosafety levels.

bioRxiv · Dec 29, 2021 · PreprintMicrobiology