Pericyte-specific vascular expression of SARS-CoV-2 receptor ACE2 - implications for microvascular inflammation and hypercoagulopathy in COVID-19
L. He, M. A. Mae, L. Muhl, Y. Sun, R. Pietila, K. Nahar, E. V. Liebanas, M. J. Fagerlund, A. Oldner, J. Liu, G. Genove, L. Zhang, Y. Xie, S. Liptidis, G. Mocci, , C. Betsholtz
The paper shows that pericytes, not endothelial cells, express ACE2 in microvessels, suggesting they may be infected in COVID-19 and contribute to microvascular inflammation and hypercoagulopathy.
bioRxiv · May 11, 2020 · PreprintPathology