K. B. Gomes

A tale of two fusion proteins: understanding the metastability of human respiratory syncytial virus and metapneumovirus and implications for rational design of uncleaved prefusion-closed trimers

The study analyzes metastability in fusion proteins of RSV and hMPV to design stable uncleaved prefusion-closed trimers for vaccine development.

Single-component multilayered self-assembling protein nanoparticles displaying extracellular domains of matrix protein 2 as a pan-influenza A vaccine

Single-component self-assembling protein nanoparticles displaying tandem M2e elicit robust and durable immunity against diverse influenza A viruses.