Author

Y.-N. Zhang

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 4 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Organism:mouse· 4 Research Focus:host-pathogen & immune response· 3 Research Focus:drug response / drug discovery· 2 Assay:proteomics· 2 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Assay:flow cytometry· 1

Frequent Co-Authors

J. Zhu· 4 shared L. He· 4 shared Y.-Z. Lee· 3 shared G. Ward· 2 shared I. A. Wilson· 2 shared J. Paynter· 2 shared K. B. Gomes· 2 shared M. Eldad· 2 shared

Activity by Year

2020-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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4 shared papersMicrobiology

J. Zhu

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

A tale of two fusion proteins: understanding the metastability of human respiratory syncytial virus and metapneumovirus and implications for rational design of uncleaved prefusion-closed trimers

Y.-Z. Lee, J. Han, Y.-N. Zhang, G. Ward, K. B. Gomes, S. Auclair, R. L. Stanfield, L. He, I. A. Wilson, J. Zhu

The study analyzes metastability in fusion proteins of RSV and hMPV to design stable uncleaved prefusion-closed trimers for vaccine development.

bioRxiv · Mar 7, 2024 · PreprintMicrobiology

Single-component multilayered self-assembling protein nanoparticles displaying extracellular domains of matrix protein 2 as a pan-influenza A vaccine

K. B. Gomes, Y.-N. Zhang, Y.-Z. Lee, M. Eldad, A. Lim, G. Ward, S. Auclair, L. He, J. Zhu

Single-component self-assembling protein nanoparticles displaying tandem M2e elicit robust and durable immunity against diverse influenza A viruses.

bioRxiv · Jun 2, 2023 · PreprintMicrobiology

Single-component multilayered self-assembling protein nanoparticles presenting glycan-trimmed uncleaved prefusion optimized envelope trimers as HIV-1 vaccine candidates

Y.-N. Zhang, J. Paynter, A. Antanasijevic, J. D. Allen, M. Eldad, Y.-Z. Lee, J. Copps, M. Newby, L. He, D. Chavez, P. Frost, A. E. Goodroe, J. W. Dutton, R. Lanford, C. Chen, , J. Zhu

Glycan trimming of HIV-1 Env immunogens improves vaccine-induced neutralizing antibody responses in small animals and primates.

bioRxiv · Jul 1, 2022Microbiology

Mechanism of a COVID-19 nanoparticle vaccine candidate that elicits a broadly neutralizing antibody response to SARS-CoV-2 variants

Y.-N. Zhang, J. Paynter, C. Sou, T. Fourfouris, Y. Wang, C. Abraham, T. Ngo, Y. Zhang, L. He, J. Zhu

A nanoparticle vaccine candidate induces broadly neutralizing antibodies against multiple SARS-CoV-2 variants through enhanced immune responses.

bioRxiv · Mar 26, 2021Immunology

Aglycone polyether ionophores as broad-spectrum agents inhibit multiple enveloped viruses including SARS-CoV-2 in vitro and successfully cure JEV infected mice

T. Liu, J.-Q. Li, M. Huang, Y.-N. Zhang, R. Liu, Z.-R. Zhang, Q.-Y. Zhang, Y. Wang, J. Liu, Z. Deng, B. Zhang, H.-Q. Ye

This study identifies aglycone polyether ionophores as broad-spectrum antivirals effective against multiple enveloped viruses, including SARS-CoV-2, and demonstrates their efficacy in curing JEV-infected mice.

bioRxiv · Oct 27, 2020 · PreprintMicrobiology