Author

Y.-Z. Lee

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Microbiology· 3 Biochemistry· 2

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 5 Research Focus:drug response / drug discovery· 2 Organism:mouse· 2 Organism:non-human primate· 2 Assay:protein structure· 2 Assay:proteomics· 2 Approach:biophysical modeling· 1 Research Focus:cell type annotation· 1

Frequent Co-Authors

J. Zhu· 3 shared L. He· 3 shared Y.-N. Zhang· 3 shared G. Ward· 2 shared I. A. Wilson· 2 shared K. B. Gomes· 2 shared M. Eldad· 2 shared S. Auclair· 2 shared

Activity by Year

2019-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

3 shared papersMicrobiology

J. Zhu

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

A tale of two fusion proteins: understanding the metastability of human respiratory syncytial virus and metapneumovirus and implications for rational design of uncleaved prefusion-closed trimers

Y.-Z. Lee, J. Han, Y.-N. Zhang, G. Ward, K. B. Gomes, S. Auclair, R. L. Stanfield, L. He, I. A. Wilson, J. Zhu

The study analyzes metastability in fusion proteins of RSV and hMPV to design stable uncleaved prefusion-closed trimers for vaccine development.

bioRxiv · Mar 7, 2024 · PreprintMicrobiology

Single-component multilayered self-assembling protein nanoparticles displaying extracellular domains of matrix protein 2 as a pan-influenza A vaccine

K. B. Gomes, Y.-N. Zhang, Y.-Z. Lee, M. Eldad, A. Lim, G. Ward, S. Auclair, L. He, J. Zhu

Single-component self-assembling protein nanoparticles displaying tandem M2e elicit robust and durable immunity against diverse influenza A viruses.

bioRxiv · Jun 2, 2023 · PreprintMicrobiology

Single-component multilayered self-assembling protein nanoparticles presenting glycan-trimmed uncleaved prefusion optimized envelope trimers as HIV-1 vaccine candidates

Y.-N. Zhang, J. Paynter, A. Antanasijevic, J. D. Allen, M. Eldad, Y.-Z. Lee, J. Copps, M. Newby, L. He, D. Chavez, P. Frost, A. E. Goodroe, J. W. Dutton, R. Lanford, C. Chen, , J. Zhu

Glycan trimming of HIV-1 Env immunogens improves vaccine-induced neutralizing antibody responses in small animals and primates.

bioRxiv · Jul 1, 2022Microbiology

Structure-based functional study of a peptide of an ecdysozoan superfamily: reveling a common molecular architecture and receptor-interacting residues

Y.-R. Chen, N.-W. Hsiao, S.-S. Huang, C.-C. Chang, Y.-Z. Lee, J.-R. Tsai, H.-C. Lin, J.-Y. Toullec, C.-Y. Lee, P.-C. Lyu

The paper functionally and structurally analyzes a neuropeptide from the CHH superfamily, revealing a conserved molecular architecture and identifying key receptor-interacting residues.

bioRxiv · Oct 29, 2020 · PreprintBiochemistry

Integrative model to coordinate the oligomerization and aggregation mechanisms of CCL5

Y.-C. Chen, S.-P. Chen, J.-Y. Li, P.-C. Chen, Y.-Z. Lee, K.-M. Li, R. Zarivach, Y.-J. Sun, S.-C. Sue

This study identifies two dimer-dimer interactions and one aggregation mechanism in CCL5 oligomerization using NMR and biophysical analyses.

bioRxiv · Sep 3, 2019Biochemistry