Author

K. B. Sharpless

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Organism:E. coli· 1 Organism:human· 1 Assay:proteomics· 1

Frequent Co-Authors

A. K. Chatterjee· 1 shared A. R. Ramos· 1 shared B. E. Dalesandro· 1 shared B. F. Cravatt· 1 shared C. J. Ackerman· 1 shared D. W. Wolan· 1 shared E. Chen· 1 shared E. N. Hampton· 1 shared

Activity by Year

2020-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperCancer Biology

A. K. Chatterjee

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2 papers

Recent·Most cited

Click-Based Determination of Accumulation of Molecules in Escherichia coli

G. M. Ongwae, Z. Liu, S. Feng, M. D. Chordia, R. Dash, Y. He, M. Sharifian Gh., B. E. Dalesandro, T. Guo, K. B. Sharpless, J. Dong, M. S. Siegrist, W. Im, M. Pires

The paper develops CHAMP, a method to measure cytosolic accumulation of azide-tagged molecules in Gram-negative bacteria, enabling high-throughput screening of over 1,000 compounds.

bioRxiv · Jun 20, 2023Microbiology

Chemical inhibition of ENL/AF9 YEATS domains in acute leukemia

L. Garnar-Wortzel, T. R. Bishop, S. Kitamura, N. Milosevich, J. N. Asiaban, X. Zhang, Q. Zheng, E. Chen, A. R. Ramos, C. J. Ackerman, E. N. Hampton, A. K. Chatterjee, T. S. Young, M. V. Hull, K. B. Sharpless, , M. A. Erb

This study identifies a potent inhibitor of the ENL/AF9 YEATS domain and demonstrates its selective suppression of ENL-dependent leukemia genes.

bioRxiv · Dec 1, 2020Cancer Biology