Author

K. Balakrishnan

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Assay:proteomics· 2 Research Focus:drug response / drug discovery· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1

Frequent Co-Authors

A. A. Jaguva Vasudevan· 1 shared A. E. Owens· 1 shared A. Sangwiman· 1 shared A. Simeonov· 1 shared B. Baljinnyam· 1 shared C. G. W. Gertzen· 1 shared C. Küstermann· 1 shared C. Münk· 1 shared

Activity by Year

2020-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperMicrobiology

A. A. Jaguva Vasudevan

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2 papers

Recent·Most cited

A real-time cellular thermal shift assay (RT-CETSA) to monitor target engagement

T. W. Sanchez, M. H. Ronzetti, A. E. Owens, M. Antony, T. Voss, E. Wallgren, D. Talley, K. Balakrishnan, G. Rai, J. J. Marugan, S. Michael, B. Baljinnyam, N. Southall, A. Simeonov, M. J. Henderson

The paper introduces RT-CETSA, a real-time cellular thermal shift assay that improves throughput and sensitivity for monitoring ligand-target engagement in cells.

bioRxiv · Jan 24, 2022 · PreprintPharmacology & Toxicology

Loop 1 of APOBEC3C regulates its antiviral activity against HIV-1

A. A. Jaguva Vasudevan, K. Balakrishnan, C. G. W. Gertzen, F. Borveto, Z. Zhang, A. Sangwiman, U. Held, C. Küstermann, S. Banerjee, G. G. Schumann, D. Häussinger, I. G. Bravo, H. Gohlke, C. Münk

This study shows that modifying loop 1 residues in APOBEC3C enhances its antiviral activity against HIV-1 and LINE-1 by improving ssDNA binding and deamination.

bioRxiv · Feb 5, 2020Microbiology