Author

K. C. Medha

Harvard University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:gene regulatory network inference· 1 Approach:genetic perturbation / CRISPR· 1 Organism:mouse· 1

Frequent Co-Authors

Amy J. WagersiD· 1 shared Amy Lam· 1 shared August D. BrattiiD· 1 shared Bryan L. PeackeriD· 1 shared Christopher L. RiosiD· 1 shared Heidi KletzieniD· 1 shared Jill Goldstein· 1 shared Kathleen A. Messemer· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperCell Biology

Amy J. WagersORCID

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1 paper

Recent·Most cited

In vivo gene disruption and homology-directed repair in muscles and muscle stem cells using CRISPR/Cas9

Bryan L. Peacker, Kuan‐Hung Lin, Amy Lam, Christopher L. Rios, Kexian Zhu, Jill Goldstein, Kathleen A. Messemer, Regan Ellis, Michael Florea, Heidi Kletzien, Naftali Horwitz, August D. Bratti, Umika S. Paul, Madeline Maier, K. C. Medha, , Amy J. Wagers

This study demonstrates CRISPR-HDR efficiency in postnatal cardiac, skeletal muscle, and muscle stem cells, showing developmental stage-dependent HDR rates and successful correction of a Dmd mutation in mdx mice.

bioRxiv · Jul 1, 2026 · PreprintCell Biology