Author
Harvard UniversityORCID 0000-0003-2714-7152Unclaimed ORCID profile · follow to get notified of new preprints
3 papers
Recent·Most cited
Di Guan, Seungsoo Kim, Karim Omar…·Yousin Suh
This study identifies UBE3C as a longevity-associated E3 ligase that maintains nuclear lamina integrity by modulating LMNB1 and LBR through selective autophagy, delaying senescence.
Bryan L. Peacker, Kuan‐Hung Lin, Amy Lam…·Amy J. Wagers
This study demonstrates CRISPR-HDR efficiency in postnatal cardiac, skeletal muscle, and muscle stem cells, showing developmental stage-dependent HDR rates and successful correction of a Dmd mutation in mdx mice.
Alexandru M. Pleşa, Sascha Jung, Helen H. Wang…·George McDonald Church
This study identifies SRSF1 as a rejuvenation factor through transcriptomic reprogramming, showing it improves cellular function and is linked to longevity.