Kuan‐Hung Lin

This study demonstrates CRISPR-HDR efficiency in postnatal cardiac, skeletal muscle, and muscle stem cells, showing developmental stage-dependent HDR rates and successful correction of a Dmd mutation in mdx mice.

This study demonstrates that single-vector adenine base editing via MyoAAV can recode a DMD-causing mutation in mice, with optimal therapeutic outcomes achieved in juvenile animals.

This study identifies TRIM28's role in satellite cell-mediated myogenesis by regulating myomixer expression and fusion pore formation, independent of phosphorylation or proliferation/differentiation.