Author

K. Dockx

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2 Cell Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Organism:mouse· 2 Assay:scRNA-seq· 2 Approach:deep learning· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1

Frequent Co-Authors

E. Van Gulck· 3 shared I. Najera· 2 shared L. Aerts· 2 shared N. Conceicao-Neto· 2 shared W. Pierson· 2 shared B. Autran· 1 shared B. De Clerck· 1 shared B. Voeten· 1 shared

Activity by Year

2023-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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3 shared papersImmunology

E. Van Gulck

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Sustained liver HBsAg loss and clonal T and B cell expansion upon therapeutic DNA vaccination require low HBsAg levels

N. Conceicao-Neto, W. Pierson, M. Vacca, M. Beyens, B. De Clerck, L. Aerts, B. Voeten, D. De Pooter, L. Verschueren, K. Dockx, M. Vandenberk, E. De Troyer, K. Verwilt, C. Van Hove, M. Verslegers, , E. Van Gulck

This study shows that sustained HBsAg loss and immune cell expansion in the liver occur after therapeutic DNA vaccination in a mouse model when HBsAg levels are low.

bioRxiv · Sep 4, 2023Immunology

AAV-HBV mouse model replicates immune exhaustion patterns of chronic HBV patients at single-cell level

N. Conceicao-Neto, Q. Han, Z. Yao, W. Pierson, Q. Wu, K. Dockx, L. Aerts, D. De Maeyer, K. Van den Berge, C. Li, G. Kukolj, R. Zhu, O. Podlaha, I. Najera, E. Van Gulck

bioRxiv · Aug 7, 2023 · PreprintImmunology

A truncated HIV Tat demonstrates potent and specific latency reversal activity

E. Van Gulck, M. Pardons, E. Nijs, N. Verheyen, K. Dockx, C. Van Den Eynde, E. Battivelli, J. Vega, E. Florence, B. Autran, N. Archin, D. M. Margolis, C. Katlama, C. Hamimi, I. Van Den Wyngaert, , D. Boden

The paper demonstrates that a truncated HIV Tat protein and mRNA can reactivate HIV-1 in latently infected T-cells as effectively as Phorbol 12-Myristate 13-Acetate without T-cell activation or significant transcriptome changes.

bioRxiv · Mar 2, 2023 · PreprintCell Biology