Amino acid substitutions in norovirus VP1 dictate cell tropism via an attachment process dependent on membrane mobility.
J. T. Mills, S. C. Minogue, J. S. Snowden, K. E. Carnahan, D. J. Rowlands, N. J. Stonehouse, C. E. Wobus, M. R. Herod
This study identifies an amino acid substitution in norovirus VP1 that enhances cellular attachment and alters tropism by affecting receptor recruitment and membrane mobility.
bioRxiv · Feb 17, 2023 · PreprintMicrobiology