Author

K. E. Knudsen

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Assay:DNA methylation· 1 Research Focus:variant calling· 1 Assay:whole-exome sequencing· 1 Assay:whole-genome sequencing· 1

Frequent Co-Authors

A. A. Shafi· 1 shared A. C. Mandigo· 1 shared A. Collazos· 1 shared A. Cooke· 1 shared A. S. Green· 1 shared A. Tomassini· 1 shared A.-L. Silva· 1 shared B. Balmforth· 1 shared

Activity by Year

2023-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperCancer Biology

A. A. Shafi

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2 papers

Recent·Most cited

ASPYRE-Lung: Validation of a simple, fast, robust and novel method for multi-variant genomic analysis of actionable NSCLC variants in tissue

R. T. Evans, E. Gillon-Zhang, J. N. Brown, K. E. Knudsen, C. King, A. S. Green, A.-L. Silva, J. M. Mordaka, R. N. Palmer, A. Tomassini, A. Collazos, C. Xyrafaki, I. Turner, C. H. Ho, D. Nugent, , R. J. Osborne

The paper validates ASPYRE-Lung, a method for detecting actionable variants in NSCLC tissue with high sensitivity, specificity, and precision.

bioRxiv · Feb 7, 2024Cancer Biology

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration-resistant prostate cancer

N. Gordon, P. T. Gallagher, N. P. Neupane, A. C. Mandigo, J. K. McCann, E. Dylgjeri, I. Vasilevskaya, C. McNair, C. J. Paller, W. K. Kelly, K. E. Knudsen, A. A. Shafi, M. J. Schiewer

This study shows that combining PARP inhibitors with pharmacological ascorbate synergistically kills castration-resistant prostate cancer cells in vitro and in vivo.

bioRxiv · Mar 23, 2023Cancer Biology