Author

A. A. Shafi

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Research Focus:cancer & tumor microenvironment· 2 Approach:experimental assay· 2 Organism:human· 2

Frequent Co-Authors

K. E. Knudsen· 2 shared M. J. Schiewer· 2 shared A. C. Mandigo· 1 shared A. Sharp· 1 shared C. J. Paller· 1 shared C. M. McNair· 1 shared C. McNair· 1 shared D. Bogdan· 1 shared

Activity by Year

2023-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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2 shared papersCancer Biology

K. E. Knudsen

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2 papers

Recent·Most cited

AR coactivators, CBP/p300, are critical mediators of DNA repair in prostate cancer

S. Sardar, C. M. McNair, L. Ravindranath, S. N. Chand, W. Yuan, D. Bogdan, J. Welti, A. Sharp, N. K. Ryan, M. J. Schiewer, E. G. DeArment, T. Janas, X. A. Su, L. M. Butler, J. S. de Bono, , A. A. Shafi

This study identifies CBP/p300 as critical for DNA repair in prostate cancer and shows that targeting it enhances therapeutic response.

bioRxiv · May 7, 2024Cancer Biology

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration-resistant prostate cancer

N. Gordon, P. T. Gallagher, N. P. Neupane, A. C. Mandigo, J. K. McCann, E. Dylgjeri, I. Vasilevskaya, C. McNair, C. J. Paller, W. K. Kelly, K. E. Knudsen, A. A. Shafi, M. J. Schiewer

This study shows that combining PARP inhibitors with pharmacological ascorbate synergistically kills castration-resistant prostate cancer cells in vitro and in vivo.

bioRxiv · Mar 23, 2023Cancer Biology