Author

C. J. Paller

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 2 Approach:experimental assay· 2 Organism:human· 2 Assay:bulk RNA-seq· 1

Frequent Co-Authors

A. A. Shafi· 1 shared A. C. Mandigo· 1 shared A. Shetty· 1 shared C. McNair· 1 shared D. Topiwala· 1 shared E. Dylgjeri· 1 shared H. Nguyen· 1 shared I. Vasilevskaya· 1 shared

Activity by Year

2023-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperCancer Biology

A. A. Shafi

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2 papers

Recent·Most cited

CRM1 regulates androgen receptor stability and impacts DNA repair pathways in prostate cancer, independent of the androgen receptor.

R. Kumar, J. Mendonca, A. Shetty, Y. Yang, O. Owoyemi, L. C. Wilson, K. Boyapati, D. Topiwala, N. Thomas, H. Nguyen, J. Luo, C. J. Paller, S. R. Denmeade, M. A. Carducci, S. K. Kachhap

This study shows CRM1 regulates androgen receptor stability and DNA repair in prostate cancer, suggesting combination therapy with CRM1 and DNA repair inhibitors could be effective.

bioRxiv · Feb 13, 2024Cancer Biology

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration-resistant prostate cancer

N. Gordon, P. T. Gallagher, N. P. Neupane, A. C. Mandigo, J. K. McCann, E. Dylgjeri, I. Vasilevskaya, C. McNair, C. J. Paller, W. K. Kelly, K. E. Knudsen, A. A. Shafi, M. J. Schiewer

This study shows that combining PARP inhibitors with pharmacological ascorbate synergistically kills castration-resistant prostate cancer cells in vitro and in vivo.

bioRxiv · Mar 23, 2023Cancer Biology