Author

R. J. Osborne

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Assay:whole-genome sequencing· 2 Research Focus:cancer & tumor microenvironment· 1 Assay:DNA methylation· 1 Research Focus:variant calling· 1 Assay:whole-exome sequencing· 1

Frequent Co-Authors

A. Collazos· 1 shared A. Cooke· 1 shared A. Noorani· 1 shared A. S. Green· 1 shared A. Tomassini· 1 shared A.-L. Silva· 1 shared B. Balmforth· 1 shared C. Alder· 1 shared

Activity by Year

2018-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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1 shared paperCancer Biology

A. Collazos

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2 papers

Recent·Most cited

ASPYRE-Lung: Validation of a simple, fast, robust and novel method for multi-variant genomic analysis of actionable NSCLC variants in tissue

R. T. Evans, E. Gillon-Zhang, J. N. Brown, K. E. Knudsen, C. King, A. S. Green, A.-L. Silva, J. M. Mordaka, R. N. Palmer, A. Tomassini, A. Collazos, C. Xyrafaki, I. Turner, C. H. Ho, D. Nugent, , R. J. Osborne

The paper validates ASPYRE-Lung, a method for detecting actionable variants in NSCLC tissue with high sensitivity, specificity, and precision.

bioRxiv · Feb 7, 2024Cancer Biology

The landscape of somatic mutation in normal colorectal epithelial cells

H. Lee-Six, P. Ellis, R. J. Osborne, M. A. Sanders, L. Moore, N. Georgakopoulos, F. Torrente, A. Noorani, M. Goddard, P. Robinson, T. H. H. Coorens, L. O'Neill, C. Alder, J. Wang, R. C. Fitzgerald, , M. R. Stratton

This study whole genome sequences normal colorectal crypts to reveal mutational processes and driver mutations in morphologically normal tissue, showing neoplastic changes are pervasive.

bioRxiv · Sep 13, 2018Cancer Biology