Author

K. E. Mahoney

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 4 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Assay:proteomics· 5 Research Focus:cell type annotation· 3 Organism:human· 3 Research Focus:protein folding & dynamics· 1

Frequent Co-Authors

S. A. Malaker· 5 shared T. M. Lucas· 3 shared C. Kwon· 2 shared C. R. Bertozzi· 2 shared K. H. Tiemeyer· 2 shared M. A. Hollenhorst· 2 shared V. Chang· 2 shared V. Rangel-Angarita· 2 shared

Activity by Year

2022-2023 · peak 4/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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5 shared papersBiochemistry

S. A. Malaker

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Author profile →

5 papers

Recent·Most cited

Xylosyltransferase Bump-and-hole Engineering to Chemically Manipulate Proteoglycans in Mammalian Cells

Z. Li, L. Di Vagno, H. Chawla, A. Ni Cheallaigh, M. Critcher, D. Sammon, D. C. Briggs, N. Chung, V. Chang, K. E. Mahoney, A. Cioce, L. D. Murphy, Y.-H. Chen, Y. Narimatsu, R. L. Miller, , B. Schumann

This paper develops a chemical genetic strategy to manipulate proteoglycan glycan attachment sites in mammalian cells using modified xylosyltransferases.

bioRxiv · Dec 20, 2023 · PreprintBiochemistry

Optimized mucin-selective enrichment strategy to probe the mucinome

K. E. Mahoney, V. Chang, T. M. Lucas, K. Maruszko, S. A. Malaker

The paper optimizes a mucin-selective enrichment strategy to improve throughput, reduce sample input, and enhance glycopeptide signal for mucinome analysis.

bioRxiv · Dec 18, 2023 · PreprintBiochemistry

False positive glycopeptide identification via in-FAIMS fragmentation

V. Rangel-Angarita, K. E. Mahoney, C. Kwon, R. Sarker, T. M. Lucas, S. A. Malaker

This study identifies a phenomenon called 'in FAIMS fragmentation' that increases spectral matches in glycopeptide analysis, highlighting potential benefits and limitations of FAIMS for O-glycoproteomics.

bioRxiv · May 28, 2023 · PreprintBiochemistry

Glycoproteomic landscape and structural dynamics of TIM family immune checkpoints enabled by mucinase SmE

J. Chongsaritsinsuk, A. D. Steigmeyer, K. E. Mahoney, M. A. Rosenfeld, T. M. Lucas, D. Ince, F. L. Kearns, A. S. Battison, M. A. Hollenhorst, J. Shon, K. H. Tiemeyer, V. Attah, C. Kwon, C. R. Bertozzi, M. J. Ferracane, , S. A. Malaker

The paper uses a mucinase to analyze glycoproteomic features of TIM family proteins and shows how glycosylation affects their structure through molecular dynamics simulations.

bioRxiv · Feb 1, 2023Cancer Biology

Comprehensive analysis of platelet glycoprotein Ibα glycosylation.

M. A. Hollenhorst, K. H. Tiemeyer, K. E. Mahoney, K. Aoki, M. Ishihara, S. C. Lowery, V. Rangel-Angarita, C. R. Bertozzi, S. A. Malaker

This study identifies O- and N-glycosites on GPIb and characterizes its glycan structures using mass spectrometry.

bioRxiv · Jul 19, 2022Biochemistry