Y. Narimatsu

Distributional shifts change the biodiversity-ecosystem stability relationship under climate change

The paper examines how distributional shifts under climate change affect biodiversity-ecosystem stability relationships by analyzing over 25 years of species data.

Xylosyltransferase Bump-and-hole Engineering to Chemically Manipulate Proteoglycans in Mammalian Cells

This paper develops a chemical genetic strategy to manipulate proteoglycan glycan attachment sites in mammalian cells using modified xylosyltransferases.

Expression of mRNAs Encoding Hypothalamic Small Proteins, Neurosecretory Protein GL and Neurosecretory Protein GM, in the Japanese Quail, Coturnix japonica

This study identifies and localizes NPGL and NPGM mRNA expression in the Japanese quail hypothalamus, showing sex-specific and fasting-responsive patterns.

Isoform-specific O-glycosylation dictates Ebola virus infectivity

This study shows that specific O-glycosylation of Ebola virus glycoprotein affects viral infectivity and identifies key host enzymes involved in this process.

Neurosecretory protein GL-induced fat accumulation is accompanied by repressing the immune-inflammatory response in the adipose tissue of mice

This study shows that short-term NPGL overexpression in mice increases fat accumulation and suppresses immune-inflammatory responses in adipose tissue.

Overexpression of the gene encoding neurosecretory protein GL precursor prevents excessive fat accumulation in the adipose tissue of mice fed a long-term high-fat diet

This study shows that overexpressing the NPGL gene in mice on a high-fat diet increases food intake and body mass but prevents excessive fat accumulation in specific adipose tissues.

Subcutaneous infusion of neurosecretory protein GL promotes fat accumulation in mice

This study shows that subcutaneous NPGL infusion in mice increases white adipose tissue fat accumulation without affecting body mass or food intake.

The half-life of the bone-derived hormone osteocalcin is regulated through O-glycosylation in mice, but not in humans

The study shows that O-glycosylation extends the half-life of mouse osteocalcin but not human osteocalcin, highlighting a species difference in hormone regulation.

Endosomal trafficking is required for glycosylation and normal maturation of the Alzheimer's-associated protein sorLA

This study shows that endosomal trafficking is essential for sorLA maturation and shedding, with immature sorLA acquiring complex N-glycans upon retrograde transport.

Glycoengineering of NK cells with glycan ligands of CD22 and selectins for B-cell lymphoma therapy

This study modifies NK cells with CD22 and selectin glycan ligands to enhance B-cell lymphoma targeting and trafficking, achieving effective tumor suppression in a xenograft model.

Estimating maximum sustainable yield of snow crab (Chionoecetes opilio) off Tohoku Japan via a state-space assessment model with time-varying natural mortality

The paper estimates the maximum sustainable yield of snow crab using a state-space model, finding that natural mortality and terminal molting probabilities have increased over time, affecting MSY estimates.