Author

R. L. Miller

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2 Microbiology· 2 Biochemistry· 1

Signature Assays, Organisms & Methods

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Organism:human· 5 Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 2 Assay:proteomics· 2 Approach:biophysical modeling· 1 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1

Frequent Co-Authors

R. Karlsson· 3 shared A. J. Ridley· 2 shared D. P. Dyer· 2 shared E. A. Yates· 2 shared J. E. Turnbull· 2 shared N. Pun· 2 shared T. A. Jowitt· 2 shared Y.-H. Chen· 2 shared

Activity by Year

2020-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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3 shared papersImmunology

R. Karlsson

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Xylosyltransferase Bump-and-hole Engineering to Chemically Manipulate Proteoglycans in Mammalian Cells

Z. Li, L. Di Vagno, H. Chawla, A. Ni Cheallaigh, M. Critcher, D. Sammon, D. C. Briggs, N. Chung, V. Chang, K. E. Mahoney, A. Cioce, L. D. Murphy, Y.-H. Chen, Y. Narimatsu, R. L. Miller, , B. Schumann

This paper develops a chemical genetic strategy to manipulate proteoglycan glycan attachment sites in mammalian cells using modified xylosyltransferases.

bioRxiv · Dec 20, 2023 · PreprintBiochemistry

Chemokines form complex signals during inflammation and disease that can be decoded by extracellular matrix proteoglycans

A. J. Ridley, Y. Ou, R. Karlsson, N. Pun, H. L. Birchenough, T. A. Jowitt, C. Lawless, R. L. Miller, D. P. Dyer

The paper analyzes chemokine gene expression across species, tissues, and diseases, showing complex patterns and demonstrates that ECM proteoglycans modulate chemokine signaling and leukocyte recruitment.

bioRxiv · Sep 20, 2022Immunology

Chemokine CXCL4 interactions with extracellular matrix proteoglycans mediate wide-spread non-receptor mediated immune cell recruitment

A. L. Gray, R. Karlsson, A. R. Roberts, A. J. Ridley, N. Pun, C. Hughes, L. Medina-Ruiz, H. Birchenough, C. Salanga, E. A. Yates, J. E. Turnbull, T. M. Handel, G. Graham, T. A. Jowitt, I. Schiessl, , D. P. Dyer

The paper shows CXCL4 binds to extracellular matrix proteoglycans, increasing vascular permeability and recruiting various leukocytes through a non-canonical mechanism.

bioRxiv · Jul 10, 2022 · PreprintImmunology

HIV proviral burden, genetic diversity and dynamics in viremic controllers who subsequently initiated suppressive antiretroviral therapy

F. H. Omondi, H. Sudderuddin, A. Shahid, N. N. Kinloch, B. R. Jones, R. L. Miller, O. Tsai, D. MacMillan, A. Trocha, M. A. Brockman, C. J. Brumme, J. B. Joy, R. Liang, B. D. Walker, Z. L. Brumme

This study characterizes proviral burden, diversity, and dynamics in viremic controllers before and after ART initiation using phylogenetic analysis and mathematical modeling.

bioRxiv · Mar 29, 2021Microbiology

Synthetic Heparan Sulfate Mimetic Pixatimod (PG545) Potently Inhibits SARS-CoV-2 By Disrupting The Spike-ACE2 interaction

S. E. Guimond, C. J. Mycroft-West, N. S. Gandhi, J. A. Tree, T. T. Le, C. M. Spalluto, M. V. Humbert, K. R. Buttigieg, N. Coombes, M. J. Elmore, K. Nystrom, J. Said, Y. X. Setoh, A. Amarilla, N. Modhiran, , J. E. Turnbull

This paper shows that pixatimod inhibits SARS-CoV-2 by disrupting the Spike-ACE2 interaction, demonstrating its potential as an anti-COVID-19 therapeutic.

bioRxiv · Jun 24, 2020Microbiology