SLP2/prohibitins aggregates and instability of the PHB complex are key elements in CHCHD10S59L-related disease
E. C. GENIN, S. Bannwarth, B. Ropert, A. Mauri-Crouzet, F. Lespinasse, G. Auge, K. Fragaki, C. Cochaud, S. Lacas-Gervais, V. Paquis-Flucklinger
The paper identifies SLP2/prohibitin aggregates and PHB complex instability as key factors in CHCHD10S59L-related disease, leading to mitochondrial dysfunction and apoptosis.
bioRxiv · May 31, 2021 · PreprintPathology