The repositioning of epigenetic probes/inhibitors identifies new anti-schistosomal lead compounds and chemotherapeutic targets
K. Whatley, G. Padalino, H. Whiteland, K. Geyer, B. Hulme, I. Chalmers, J. Forde-Thomas, S. Ferla, A. Brancale, K. F. Hoffmann
This paper screens epigenetic probes/inhibitors against Schistosoma mansoni and identifies compounds targeting histone methylation/demethylation processes as potential anti-schistosomal agents.
bioRxiv · Aug 8, 2019Zoology