Author

K. H. C. Gowers

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Cell Biology· 1

Signature Assays, Organisms & Methods

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Organism:human· 3 Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Approach:statistical model· 2 Research Focus:clustering· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

R. E. Hynds· 3 shared S. M. Janes· 3 shared A. Pennycuick· 2 shared C. Denais· 2 shared C. Swanton· 2 shared D. R. Pearce· 2 shared N. McGranahan· 2 shared S. A. Quezada· 2 shared

Activity by Year

2019-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersCancer Biology

R. E. Hynds

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3 papers

Recent·Most cited

Cancer BiologybioRxivJan 6, 2023

Genomic evolution of non-small cell lung cancer patient-derived xenograft models

R. E. Hynds, A. Huebner, D. R. Pearce…·C. Swanton

This study examines how well PDX models capture intratumour heterogeneity in NSCLC, finding that most models originate from a single subclone but regional models can capture diversity.

DOI 10.1038/s41467-024-47547-3

humanwhole-exome sequencing

𝕏 PostBluesky

Cell BiologybioRxivApr 20, 2020

Cell-intrinsic differences between human airway epithelial cells from children and adults

E. F. Maughan, R. E. Hynds, A. Pennycuick…·S. M. Janes

The paper compares airway epithelial cells from children and adults, finding intrinsic differences in transcriptional profiles and regenerative capacity.

DOI 10.1016/j.isci.2022.105409

humanbulk RNA-seq

𝕏 PostBluesky

Cancer BiologybioRxivNov 10, 2019

Immune surveillance in clinical regression of pre-invasive squamous cell lung cancer

A. Pennycuick, V. H. Teixeira, K. AbdulJabbar…·S. M. Janes

The paper investigates immune surveillance in pre-invasive squamous cell lung cancer, finding that regressive lesions have more immune infiltration and distinct molecular profiles compared to progressive lesions.

DOI 10.1158/2159-8290.cd-19-1366

humanbulk RNA-seq

𝕏 PostBluesky