Author

A. Huebner

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 3 Microbiology· 2 Cell Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 4 Approach:experimental assay· 4 Organism:human· 4 Research Focus:clustering· 2 Assay:metagenomics· 2 Approach:statistical model· 2 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:differential expression· 1

Frequent Co-Authors

C. Swanton· 3 shared D. R. Pearce· 3 shared R. E. Hynds· 3 shared A. U. Akarca· 2 shared C. Warinner· 2 shared D. A. Moore· 2 shared M. Sivakumar· 2 shared S. M. Janes· 2 shared

Activity by Year

2017-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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Curved chords = mutual co-authorship

3 shared papersCancer Biology

C. Swanton

Mutual co-authors in cluster

Author profile →

6 papers

Recent·Most cited

Imaging the master regulator of the antioxidant response in non-small cell lung cancer with positron emission tomography

H. E. Greenwood, R. S. Edwards, W. E. Tyrrell, A. R. Barber, F. Baark, M. Tanc, E. Khalil, A. Falzone, N. P. Ward, J. M. DeBlasi, L. Torrente, D. R. Pearce, G. Firth, L. M. Smith, O. Vilhelmsson Timmermand, , T. H. Witney

This study uses PET imaging to assess NRF2 activation in NSCLC, showing [18F]FSPG as a marker of therapeutic resistance and a potential target for treatment.

bioRxiv · Dec 16, 2023Cancer Biology

Phenotyping of lymphoproliferative tumours generated in xenografts of non-small cell lung cancer

D. R. Pearce, A. U. Akarca, R. P. H. De Maeyer, E. Kostina, A. Huebner, M. Sivakumar, T. Karasaki, K. Shah, S. M. Janes, N. E. McGranahan, V. Reddy, A. Akbar, D. A. Moore, T. Marafioti, C. Swanton, R. E. Hynds

The paper identifies lymphoproliferative B cells in NSCLC PDX models and develops a tool for generating pathology overview figures.

bioRxiv · Jan 24, 2023Cancer Biology

Genomic evolution of non-small cell lung cancer patient-derived xenograft models

R. E. Hynds, A. Huebner, D. R. Pearce, A. U. Akarca, D. A. Moore, S. Ward, K. H. C. Gowers, T. Karasaki, M. S. Hill, M. Al Bakir, G. A. Wilson, O. Pich, M. Sivakumar, A. Ben Aissa, E. Gronroos, , C. Swanton

This study examines how well PDX models capture intratumour heterogeneity in NSCLC, finding that most models originate from a single subclone but regional models can capture diversity.

bioRxiv · Jan 6, 2023Cancer Biology

A glimpse of the paleome in endolithic microbial communities

C.-E. Wegner, R. Stahl, I. M. Velsko, A. Huebner, Z. Fagernaes, C. Warinner, R. Lehmann, T. Ritschel, K. U. Totsche, K. Kuesel

The paper investigates endolithic microbial communities in rock samples, recovering DNA and revealing paleome signatures with increased chemolithoautotrophs and aromatic hydrocarbon breakdown potential.

bioRxiv · Sep 23, 2022Microbiology

CoproID predicts the source of coprolites and paleofeces using microbiome composition and host DNA content

M. Borry, B. Cordova, A. Perri, M. C. Wibowo, T. Honap, W. T. J. Ko, J. Yu, K. Britton, L. G. Flink, R. C. Power, I. Stuijts, D. S. Garcia, C. A. Hofman, R. W. Hagan, T. S. Kagone, , C. Warinner

The paper introduces a method to determine the source of coprolites and paleofeces using microbiome composition and host DNA content, distinguishing between human, canine, and non-fecal materials.

bioRxiv · Jan 15, 2020Microbiology

Compensation For Chronic Oxidative Stress In ALADIN Null Mice

R. Jühlen, M. Peitzsch, S. Gärtner, D. Landgraf, G. Eisenhofer, A. Huebner, K. Koehler

This study shows ALADIN null mice do not develop a triple A-like phenotype under chronic oxidative stress, indicating a compensatory mechanism in glutathione metabolism.

bioRxiv · Jul 17, 2017Cell Biology