Author

K. Hosseini

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 5

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Research Focus:cell signaling & trafficking· 4 Organism:human· 4 Research Focus:cancer & tumor microenvironment· 2 Research Focus:cell type annotation· 1 Assay:fluorescence / live-cell microscopy· 1 Approach:genetic perturbation / CRISPR· 1

Frequent Co-Authors

E. Fischer-Friedrich· 5 shared A. Frenzel· 3 shared C. Werner· 2 shared A. Taubenberger· 1 shared I. Poser· 1 shared L. Sbosny· 1 shared P. Trus· 1 shared

Activity by Year

2020-2023 · peak 3/yr

Co-Author Collaboration Network

7 top collaborators · 11 mutual co-author links

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5 shared papersBiophysics

E. Fischer-Friedrich

Mutual co-authors in cluster

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5 papers

Recent·Most cited

EMT induces cell-cycle-dependent changes of Rho GTPases and downstream effectors

K. Hosseini, A. Frenzel, E. Fischer-Friedrich

The paper shows EMT in breast cancer cells causes cell-cycle-dependent changes in Rho GTPases and downstream effectors, proposing two new signalling pathways.

bioRxiv · Feb 2, 2023 · PreprintBiophysics

Skin epithelial cells change their mechanics and proliferation upon Snail-mediated EMT signalling

K. Hosseini, P. Trus, A. Frenzel, C. Werner, E. Fischer-Friedrich

This study shows that Snail-mediated EMT in skin epithelial cells alters cellular mechanics, mitotic rounding, and proliferation, with implications for skin tumor progression.

bioRxiv · Feb 1, 2022Biophysics

EMT changes actin cortex rheology in a cell-cycle dependent manner

K. Hosseini, A. Frenzel, E. Fischer-Friedrich

This study examines how EMT affects actin cortex rheology in human epithelial cells, finding cell-cycle dependent softening in interphase and stiffening in mitosis.

bioRxiv · Dec 15, 2020Biophysics

Binding dynamics of α-actinin-4 in dependence of actin cortex tension

K. Hosseini, L. Sbosny, I. Poser, E. Fischer-Friedrich

The paper quantifies how -actinin-4 binding dynamics depend on actin cortex tension in live cells, showing it acts as a catch bond under physiological tension.

Biophysical Journal · Sep 1, 2020Peer-reviewedBiophysics

EMT-induced cell mechanical changes enhance mitotic rounding strength

K. Hosseini, A. Taubenberger, C. Werner, E. Fischer-Friedrich

This study shows that EMT in breast epithelial cells enhances mitotic rounding strength through changes in Rho GTPase activity, aiding cancer cells in mitosis under mechanical stress.

bioRxiv · May 19, 2020Biophysics