Author

K. J. l. C. Karottki

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 2

Signature Assays, Organisms & Methods

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Research Focus:gene regulatory network inference· 2 Approach:genetic perturbation / CRISPR· 2 Organism:mouse· 2 Research Focus:cell type annotation· 1 Research Focus:perturbation response prediction· 1

Frequent Co-Authors

G. M. Lee· 2 shared H. F. Kildegaard· 2 shared H. Hefzi· 2 shared J. S. Lee· 2 shared L. E. Pedersen· 2 shared N. E. Lewis· 2 shared A. Thomas· 1 shared C. Joshi· 1 shared

Activity by Year

2020-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersBioengineering

G. M. Lee

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2 papers

Recent·Most cited

BioengineeringbioRxivDec 13, 2022

Identification of hyperosmotic stress-responsive genes in Chinese hamster ovary cells via genome-wide virus-free CRISPR/Cas9 screening

S. H. Kim, S. Shin, M. Baek…·G. M. Lee

The paper identifies hyperosmotic stress-responsive genes in CHO cells using CRISPR/Cas9 screening and validates their role in stress resistance and protein production.

DOI 10.1016/j.ymben.2023.09.006

mousegenetic perturbation / CRISPR

𝕏 PostBluesky

BioengineeringbioRxivMay 7, 2020

A metabolic CRISPR-Cas9 screen in Chinese hamster ovary cells identifies glutamine-sensitive genes

K. J. l. C. Karottki, H. Hefzi, S. Li…·N. E. Lewis

The paper uses a CRISPR-Cas9 screen in Chinese hamster ovary cells to identify glutamine-sensitive genes, revealing a novel lipase involved in TCA cycle regulation.

DOI 10.1016/j.ymben.2021.03.017

mousegenetic perturbation / CRISPR

𝕏 PostBluesky