Author

K. Jaczynska

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Biophysics· 1

Signature Assays, Organisms & Methods

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Research Focus:protein folding & dynamics· 2 Approach:biophysical modeling· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:chromatin & epigenetic regulation· 1 Approach:experimental assay· 1 Organism:human· 1 Assay:proteomics· 1

Frequent Co-Authors

J. Rizo· 2 shared C. Rosenmund· 1 shared J. Gu· 1 shared L. Sari· 1 shared L. Sutherland· 1 shared M. Kato· 1 shared M. M. Lin· 1 shared S. McKnight· 1 shared

Activity by Year

2023-2023 · peak 2/yr

Co-Author Collaboration Network

9 top collaborators · 21 mutual co-author links

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2 shared papersBiophysics

J. Rizo

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2 papers

Recent·Most cited

Molecular mechanism underlying SNARE-mediated membrane fusion enlightened by all-atom molecular dynamics simulations

J. Rizo, L. Sari, K. Jaczynska, C. Rosenmund, M. M. Lin

This study uses molecular dynamics simulations to propose a mechanism for SNARE-mediated membrane fusion, emphasizing local molecular events over general membrane properties.

bioRxiv · Nov 21, 2023 · PreprintBiophysics

Oxidative regulation of TDP-43 self-association by a beta-to-alpha conformational switch

J. Gu, X. Zhou, L. Sutherland, M. Kato, K. Jaczynska, J. Rizo, S. McKnight

This paper shows that oxidative modification of TDP-43's low complexity domain induces a beta-to-alpha conformational switch, disrupting self-association and phase separation.

bioRxiv · Aug 29, 2023 · PreprintBiochemistry