J. Cotton

Efficient and reproducible generation of human iPSC-derived cardiomyocytes using a stirred bioreactor

This paper describes a method to generate high-purity, scalable human iPSC-derived cardiomyocytes using a bioreactor, showing improved viability, function, and consistency compared to traditional methods.

Parasite hybridization promotes spreading of endosymbiotic viruses

This study shows that parasite hybridization in cutaneous leishmaniasis increases the spread of endosymbiotic viruses, contributing to disease severity.

Mucus production, host-microbiome interactions, hormone sensitivity, and innate immune responses modeled in human cervix chips

This paper develops human cervical Organ Chip models to study mucus production, host-microbiome interactions, and immune responses, showing they mimic in vivo conditions and respond to microbiome changes.

Strongyle-resistant sheep express their potential across environments and leave limited scope for parasite plasticity

The paper breeds sheep resistant to parasites and finds that resistance remains stable across environments but is affected by specific parasite infections.