Author

K. Kalesh

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Microbiology· 3 Biochemistry· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Organism:human· 4 Assay:proteomics· 4 Research Focus:cell type annotation· 3 Approach:statistical model· 3 Approach:deep learning· 2 Approach:experimental assay· 1 Research Focus:protein folding & dynamics· 1

Frequent Co-Authors

P. W. Denny· 3 shared A. J. Borg· 1 shared A. K. L. Leung· 1 shared A. P. Snijders· 1 shared B. S. Mantilla· 1 shared D. O. Haskard· 1 shared E. O. J. Porta· 1 shared J. Choudhary· 1 shared

Activity by Year

2019-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 16 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

3 shared papersMicrobiology

P. W. Denny

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Inhibition of HSP90 distinctively modulates the global phosphoproteome of Leishmania mexicana developmental stages

E. O. J. Porta, L. Gao, P. W. Denny, P. G. Steel, K. Kalesh

This study identifies how HSP90 inhibition differentially affects the phosphoproteome of Leishmania mexicana across life cycle stages, revealing distinct molecular responses in promastigotes and amastigotes.

bioRxiv · Jul 19, 2023 · PreprintMicrobiology

Transcriptome-wide identification of coding and noncoding RNA-binding proteins defines the comprehensive RNA interactome of Leishmania mexicana

K. Kalesh, W. Wei, B. S. Mantilla, T. I. Roumeliotis, J. Choudhary, P. W. Denny

This study identifies 2,417 RNA-binding proteins in Leishmania mexicana, including novel non-poly(A)-RNA-binding proteins, and reveals their roles in RNA-protein interactions and regulation of the protein kinome.

bioRxiv · Dec 8, 2021Microbiology

A BONCAT-iTRAQ method enables temporally resolved quantitative profiling of newly synthesised proteins in Leishmania mexicana parasites during starvation

K. Kalesh, P. W. Denny

This paper introduces a BONCAT-iTRAQ method to profile newly synthesized proteins in Leishmania mexicana during starvation, identifying 166 NSPs and showing time-dependent changes in translation regulators.

PLOS Neglected Tropical Diseases · Dec 19, 2019Peer-reviewedMicrobiology

An Integrated Chemical Proteomics Approach for Quantitative Profiling of Intracellular ADP-Ribosylation

K. Kalesh, S. Lukauskas, A. J. Borg, A. P. Snijders, A. K. L. Leung, D. O. Haskard, P. A. DiMaggio

This study develops a chemical proteomics method to profile ADP-ribosylation in live cells and quantifies protein responses to PARP inhibitors.

bioRxiv · Mar 5, 2019Biochemistry