Author

A. K. L. Leung

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Cancer Biology· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Assay:proteomics· 3 Approach:experimental assay· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1 Approach:deep learning· 1 Assay:DNA methylation· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

A. Gilman· 1 shared A. J. Borg· 1 shared A. K. Jayabalan· 1 shared A. Korotkov· 1 shared A. Maslov· 1 shared A. P. Snijders· 1 shared A. Patel· 1 shared A. Williams· 1 shared

Activity by Year

2019-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 22 mutual co-author links

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1 shared paperCancer Biology

A. Gilman

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

DNA repair and anti-cancer mechanisms in the longest-living mammal: the bowhead whale

D. Firsanov, M. Zacher, X. Tian, Y. Zhao, T. L. Sformo, G. Tombline, S. A. Biashad, A. Gilman, N. Hamilton, A. Patel, M. Straight, M. Lee, J. Y. Lu, E. Haseljic, A. Williams, , Gladyshev

This study investigates DNA repair mechanisms in bowhead whales, showing their high efficiency and accuracy in repairing DNA damage, which may explain their long lifespan without cancer.

bioRxiv · May 7, 2023 · PreprintCancer Biology

Alphavirus nsP3 ADP-ribosylhydrolase Activity Disrupts Stress Granule Formation

A. K. Jayabalan, D. E. Griffin, A. K. L. Leung

This study shows that alphavirus nsP3 disrupts stress granule formation by removing ADP-ribosylation from G3BP1 and altering translation factor localization.

bioRxiv · Jun 20, 2019 · PreprintCell Biology

An Integrated Chemical Proteomics Approach for Quantitative Profiling of Intracellular ADP-Ribosylation

K. Kalesh, S. Lukauskas, A. J. Borg, A. P. Snijders, A. K. L. Leung, D. O. Haskard, P. A. DiMaggio

This study develops a chemical proteomics method to profile ADP-ribosylation in live cells and quantifies protein responses to PARP inhibitors.

bioRxiv · Mar 5, 2019Biochemistry