Author

K. M. Grzes

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:mouse· 4 Research Focus:cell type annotation· 3 Approach:experimental assay· 3 Assay:bulk RNA-seq· 2 Research Focus:cell signaling & trafficking· 2 Approach:statistical model· 2 Research Focus:clustering· 1 Research Focus:differential expression· 1

Frequent Co-Authors

A. M. Kabat· 4 shared D. E. Sanin· 4 shared E. J. Pearce· 4 shared E. L. Pearce· 4 shared A. Castoldi· 3 shared G. Caputa· 3 shared N. Rana· 3 shared A. Hackl· 2 shared

Activity by Year

2021-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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4 shared papersImmunology

A. M. Kabat

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Prostaglandin E2 controls the metabolic adaptation of T cells to the intestinal microenvironment

M. Villa, D. E. Sanin, P. Apostolova, M. Corrado, A. M. Kabat, C. Cristinzio, A. Regina, G. Carrizo, N. Rana, M. A. Stanczak, F. Baixauli, K. M. Grzes, J. Cupovic, F. Solagna, A. Hackl, , E. L. Pearce

This study identifies a PGE2-autophagy-glutathione axis that enables CD8+ T cells to adapt metabolically to the intestinal microenvironment.

bioRxiv · Mar 13, 2023 · PreprintImmunology

HIGHLY PHAGOCYTIC LIPID-ASSOCIATED MACROPHAGES (LAMs) ARE INCREASED IN COLONIC LAMINA PROPRIA IN OBESITY

A. Castoldi, D. E. Sanin, N. v. T. Bakker, C. F. Aguiar, L. d. B. Monteiro, N. Rana, K. M. Grzes, A. M. Kabat, J. Curtis, A. M. Cameron, G. Caputa, T. A. de Souza, F. O. Souto, J. M. Buescher, J. E. Hicks, , N. O. S. Camara

The paper identifies obesity-induced lipid-associated macrophages (LAMs) in the colonic lamina propria, showing increased phagocytic activity and metabolic changes.

bioRxiv · Dec 20, 2022Immunology

Resident T cells orchestrate adipose tissue remodeling in a site peripheral to infection

A. M. Kabat, A. Hackl, D. E. Sanin, P. Zeis, K. M. Grzes, F. Baixauli, R. Kyle, G. Caputa, J. Edwards-Hicks, M. Villa, N. Rana, J. D. Curtis, A. Castoldi, J. Cupovic, L. Dreesen, , E. J. Pearce

The paper shows that Th2 lymphocytes in mesenteric adipose tissue interact with stromal cells to influence adiposity during helminth infection.

bioRxiv · Feb 24, 2022 · PreprintImmunology

Predictive framework of macrophage activation

D. E. Sanin, Y. Ge, E. Marinkovic, A. M. Kabat, A. Castoldi, G. Caputa, K. M. Grzes, J. D. Curtis, S. Willenborg, S. Dichtl, S. Reinhardt, A. Dahl, E. L. Pearce, S. A. Eming, A. Gerbaulet, , E. J. Pearce

The paper establishes a common framework for macrophage activation by identifying conserved transcriptional profiles across tissues and conditions.

bioRxiv · Aug 2, 2021Immunology