Author

G. Caputa

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 4

Signature Assays, Organisms & Methods

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Organism:mouse· 4 Approach:experimental assay· 3 Research Focus:cell type annotation· 2 Research Focus:host-pathogen & immune response· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:clustering· 1 Research Focus:differential expression· 1

Frequent Co-Authors

A. Castoldi· 4 shared D. E. Sanin· 4 shared E. J. Pearce· 4 shared E. L. Pearce· 4 shared A. M. Kabat· 3 shared K. M. Grzes· 3 shared N. Rana· 3 shared A. M. Cameron· 2 shared

Activity by Year

2020-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 44 mutual co-author links

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4 shared papersImmunology

A. Castoldi

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Author profile →

4 papers

Recent·Most cited

HIGHLY PHAGOCYTIC LIPID-ASSOCIATED MACROPHAGES (LAMs) ARE INCREASED IN COLONIC LAMINA PROPRIA IN OBESITY

A. Castoldi, D. E. Sanin, N. v. T. Bakker, C. F. Aguiar, L. d. B. Monteiro, N. Rana, K. M. Grzes, A. M. Kabat, J. Curtis, A. M. Cameron, G. Caputa, T. A. de Souza, F. O. Souto, J. M. Buescher, J. E. Hicks, , N. O. S. Camara

The paper identifies obesity-induced lipid-associated macrophages (LAMs) in the colonic lamina propria, showing increased phagocytic activity and metabolic changes.

bioRxiv · Dec 20, 2022Immunology

Resident T cells orchestrate adipose tissue remodeling in a site peripheral to infection

A. M. Kabat, A. Hackl, D. E. Sanin, P. Zeis, K. M. Grzes, F. Baixauli, R. Kyle, G. Caputa, J. Edwards-Hicks, M. Villa, N. Rana, J. D. Curtis, A. Castoldi, J. Cupovic, L. Dreesen, , E. J. Pearce

The paper shows that Th2 lymphocytes in mesenteric adipose tissue interact with stromal cells to influence adiposity during helminth infection.

bioRxiv · Feb 24, 2022 · PreprintImmunology

Predictive framework of macrophage activation

D. E. Sanin, Y. Ge, E. Marinkovic, A. M. Kabat, A. Castoldi, G. Caputa, K. M. Grzes, J. D. Curtis, S. Willenborg, S. Dichtl, S. Reinhardt, A. Dahl, E. L. Pearce, S. A. Eming, A. Gerbaulet, , E. J. Pearce

The paper establishes a common framework for macrophage activation by identifying conserved transcriptional profiles across tissues and conditions.

bioRxiv · Aug 2, 2021Immunology

Triacylglycerol synthesis enhances macrophage inflammatory function

A. Castoldi, L. B. Monteiro, N. van Teijlingen Bakker, D. E. Sanin, N. Rana, M. Corrado, A. M. Cameron, F. Hassler, M. Matsushita, G. Caputa, R. I. I. Klein Geltink, J. Buscher, J. Edwards-Hicks, E. L. Pearce, E. J. Pearce

This study shows that triacylglycerol synthesis in macrophages is essential for inflammatory function, as inhibiting it reduces proinflammatory cytokines and phagocytic capacity.

bioRxiv · Feb 3, 2020Immunology