Author

A. Gerbaulet

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 5 Immunology· 2

Signature Assays, Organisms & Methods

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Organism:mouse· 7 Research Focus:cell type annotation· 5 Approach:experimental assay· 5 Assay:bulk RNA-seq· 2 Research Focus:cancer & tumor microenvironment· 2 Research Focus:cell signaling & trafficking· 2 Approach:genetic perturbation / CRISPR· 2 Research Focus:host-pathogen & immune response· 2

Frequent Co-Authors

A. Roers· 5 shared A. Dahl· 3 shared S. Reinhardt· 3 shared T. Grinenko· 3 shared Y. Ge· 3 shared B. Wielockx· 2 shared C. M. Munz· 2 shared I. Glauche· 2 shared

Activity by Year

2018-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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5 shared papersCell Biology

A. Roers

Mutual co-authors in cluster

Author profile →

7 papers

Recent·Most cited

CD38 promotes hematopoietic stem cell dormancy via c-Fos

L. Ibneeva, S. P. Singh, A. Sinha, S. E. Eski, R. Wehner, L. Rupp, J. A. Perez-Valencia, A. Gerbaulet, S. Reinhardt, M. Wobus, M. Bonin, J. Sancho, F. E. Lund, A. Dahl, M. Schmitz, , T. Grinenko

This study identifies CD38 as a marker for dormant hematopoietic stem cells and shows it promotes dormancy through the cADPR/Ca2+/c-Fos/p57Kip2 pathway.

bioRxiv · Feb 8, 2023 · PreprintCell Biology

Emergency hematopoiesis proceeds without contribution of hematopoietic stem cells

C. M. Munz, N. Dressel, M. Chen, T. Grinenko, A. Roers, A. Gerbaulet

This study shows that hematopoietic stem cells (HSCs) do not contribute to mature blood cell regeneration during common emergencies like inflammation or blood loss.

bioRxiv · Oct 5, 2022Cell Biology

Clearance of genome-damaged cells from the hematopoietic system via p53 without contribution by the cGAS/STING axis

N. Dressel, L. Natusch, C. Munz, S. Costas-Ramon, M. N. F. Morcos, A. Loff, B. Hiller, H. Luksch, A. Roesen-Wolff, A. Roers, R. Behrendt, A. Gerbaulet

This study shows that p53 clears genome-damaged hematopoietic cells without needing the cGAS/STING pathway, and that cGAS/STING is not required for coping with DNA damage or preventing leukemia in RER-deficient conditions.

bioRxiv · Jun 24, 2022 · PreprintCell Biology

cGAS/STING-DEPENDENT SENSING OF ENDOGENOUS RNA

T. Schumann, S. C. Ramon, N. Schubert, M. A. Mayo, M. Hega, S.-R. Ada, L. Sydow, M. Hajikazemi, Y. Ge, M. Badstübner, S. Lienenklaus, B. Utess, L. Muhandes, M. Haase, L. Müller, , R. Behrendt

The paper shows that loss of SAMHD1 leads to chronic DNA damage and cGAS/STING-dependent type I interferon production in mice, linking it to autoimmunity and cancer.

bioRxiv · May 16, 2022Immunology

Predictive framework of macrophage activation

D. E. Sanin, Y. Ge, E. Marinkovic, A. M. Kabat, A. Castoldi, G. Caputa, K. M. Grzes, J. D. Curtis, S. Willenborg, S. Dichtl, S. Reinhardt, A. Dahl, E. L. Pearce, S. A. Eming, A. Gerbaulet, , E. J. Pearce

The paper establishes a common framework for macrophage activation by identifying conserved transcriptional profiles across tissues and conditions.

bioRxiv · Aug 2, 2021Immunology

Proliferative behavior of hematopoietic stem cells revisited: No evidence for mitotic memory

M. N. F. Morcos, T. Zerjatke, I. Glauche, C. M. Munz, Y. Ge, A. Petzold, S. Reinhardt, A. Dahl, N. Anstee, R. Bogeska, M. Milsom, P. Saewen, H. Wan, D. Bryder, A. Roers, A. Gerbaulet

The paper revisits the proliferative behavior of hematopoietic stem cells (HSCs) and finds no evidence for mitotic memory or permanent quiescence after few divisions.

bioRxiv · Aug 28, 2019Cell Biology

Hematopoietic stem cells differentiate into restricted myeloid progenitors before cell division

T. Grinenko, A. Eugster, L. Thielecke, B. Ramasz, A. Krueger, S. Dietz, I. Glauche, A. Gerbaulet, M. von Bonin, O. Basak, H. Clevers, T. Chavakis, B. Wielockx

This study shows hematopoietic stem cells can differentiate into restricted progenitors without dividing or entering the S phase, indicating fate decisions are uncoupled from cell division.

bioRxiv · Jan 30, 2018Cell Biology