Author

J. M. Buescher

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Research Focus:cell type annotation· 3 Approach:experimental assay· 3 Organism:mouse· 3 Assay:bulk RNA-seq· 2 Research Focus:cell signaling & trafficking· 2 Research Focus:differential expression· 2 Assay:metabolomics· 2 Approach:statistical model· 2

Frequent Co-Authors

D. E. Sanin· 3 shared E. J. Pearce· 3 shared E. L. Pearce· 3 shared A. M. Kabat· 2 shared D. J. Puleston· 2 shared F. Baixauli· 2 shared K. M. Grzes· 2 shared M. Villa· 2 shared

Activity by Year

2020-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 42 mutual co-author links

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3 shared papersImmunology

D. E. Sanin

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Prostaglandin E2 controls the metabolic adaptation of T cells to the intestinal microenvironment

M. Villa, D. E. Sanin, P. Apostolova, M. Corrado, A. M. Kabat, C. Cristinzio, A. Regina, G. Carrizo, N. Rana, M. A. Stanczak, F. Baixauli, K. M. Grzes, J. Cupovic, F. Solagna, A. Hackl, , E. L. Pearce

This study identifies a PGE2-autophagy-glutathione axis that enables CD8+ T cells to adapt metabolically to the intestinal microenvironment.

bioRxiv · Mar 13, 2023 · PreprintImmunology

HIGHLY PHAGOCYTIC LIPID-ASSOCIATED MACROPHAGES (LAMs) ARE INCREASED IN COLONIC LAMINA PROPRIA IN OBESITY

A. Castoldi, D. E. Sanin, N. v. T. Bakker, C. F. Aguiar, L. d. B. Monteiro, N. Rana, K. M. Grzes, A. M. Kabat, J. Curtis, A. M. Cameron, G. Caputa, T. A. de Souza, F. O. Souto, J. M. Buescher, J. E. Hicks, , N. O. S. Camara

The paper identifies obesity-induced lipid-associated macrophages (LAMs) in the colonic lamina propria, showing increased phagocytic activity and metabolic changes.

bioRxiv · Dec 20, 2022Immunology

Polyamine Metabolism Regulates the T Cell Epigenome Through Hypusination

D. J. Puleston, F. Baixauli, D. E. Sanin, M. Villa, A. Kabat, M. M. Kaminski, H. Weiss, K. Grzes, L. J. Flachsmann, C. S. Field, M. Stanckzak, L. Schimmelpfennig, F. Hassler, C. Wang, N. Yosef, , E. L. Pearce

This study shows that polyamine metabolism, specifically through hypusination, is essential for maintaining T cell subset identity by regulating the epigenome and transcriptional programs.

bioRxiv · Jan 24, 2020 · PreprintImmunology