Author

K. M. Ottemann

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Microbiology· 6

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 5 Research Focus:host-pathogen & immune response· 5 Organism:human· 3 Organism:mouse· 3 Research Focus:cell type annotation· 2 Assay:proteomics· 2 Assay:bulk RNA-seq· 1 Research Focus:clustering· 1

Frequent Co-Authors

C. Yang· 2 shared K. S. Johnson· 2 shared A. Roujeinikova· 1 shared A. Worthington· 1 shared B. Elgamoudi· 1 shared C. J. Day· 1 shared D. Keilberg· 1 shared E. G. Sweeney· 1 shared

Activity by Year

2017-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersMicrobiology

C. Yang

Mutual co-authors in cluster

Author profile →

6 papers

Recent·Most cited

Helicobacter chronic stage inflammation undergoes fluctuations that are altered in tlpA mutants

K. S. Johnson, C. Yang, J. E. Carter, A. Worthington, E. K. Robinson, R. Lopez Magana, F. Salgado, I. Arnold, K. M. Ottemann

This study shows that H. pylori chronic inflammation fluctuates over time, and tlpA mutants alter these dynamics without affecting colonization levels in later stages.

bioRxiv · Aug 1, 2022 · PreprintMicrobiology

FliL has a conserved function in diverse microbes to negatively modulate motor output via its N-terminal region

X. Liu, A. Roujeinikova, K. M. Ottemann

The paper reanalyzes fliL mutant studies and finds that retention of the N-terminal region, including the transmembrane helix, negatively modulates bacterial motor output.

bioRxiv · May 17, 2022 · PreprintMicrobiology

The immunomodulatory dCache chemoreceptor TlpA of Helicobacter pylori binds multiple attractant and antagonistic ligands via distinct sites

K. S. Johnson, B. Elgamoudi, F. E.- C. Jen, C. J. Day, E. G. Sweeney, M. L. Pryce, K. Guillemin, T. Haselhorst, V. Korolik, K. M. Ottemann

This study identifies multiple ligands bound by the H. pylori chemoreceptor TlpA, revealing both attractant and antagonist functions through distinct binding sites.

bioRxiv · Apr 7, 2021Microbiology

Gastric metabolomics analysis supports H. pyloris catabolism of organic and amino acids in both the corpus and antrum

D. Keilberg, N. Steele, S. Fan, C. Yang, Y. Zavros, K. M. Ottemann

This study compares metabolomics profiles in mouse gastric corpus and antrum organoids and tissue, revealing distinct metabolic differences and H. pylori nutrient utilization patterns.

bioRxiv · Jul 1, 2020 · PreprintMicrobiology

The Helicobacter pylori biofilm involves a multi-gene stress-biased response including a structural role for flagella

S. Hathroubi, J. Zerebinski, K. M. Ottemann

This study identifies a multi-gene stress-biased response in H. pylori biofilm formation, with flagella playing a structural role in the biofilm matrix.

bioRxiv · Sep 9, 2018Microbiology

Chemotaxis allows bacteria to overcome host-generated reactive oxygen species that constrain gland colonization

K. D. Collins, S. Hu, H. Grasberger, J. Y. Kao, K. M. Ottemann

This study shows that Helicobacter pylori uses chemotaxis to overcome host-generated reactive oxygen species, enabling colonization of stomach glands.

bioRxiv · Nov 10, 2017Microbiology