Author

Y. Zavros

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Cell Biology· 1 Microbiology· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:human· 3 Organism:mouse· 2 Assay:organoid / primary culture· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:development & morphogenesis· 1 Research Focus:differential expression· 1

Frequent Co-Authors

C. A. Thorne· 2 shared J. Chakrabarti· 2 shared K. W. Pond· 2 shared A. E. Greenstein· 1 shared A. G. Moraitis· 1 shared A. L. Paek· 1 shared A. Livolsi· 1 shared A. S. Little· 1 shared

Activity by Year

2020-2022 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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2 shared papersPhysiology

C. A. Thorne

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Genetically Engineered Human Pituitary Corticotroph Tumor Organoids Exhibit Divergent Responses To Glucocorticoid Receptor Modulators

S. Mallick, J. Chakrabarti, J. Eschbacher, A. G. Moraitis, A. E. Greenstein, J. Churko, K. W. Pond, A. Livolsi, C. A. Thorne, A. S. Little, K. C. Yuen, Y. Zavros

This study uses PitNET organoids to show relacorilant reduces tumor growth and induces apoptosis better than mifepristone, and enhances response to somatostatin analogs.

bioRxiv · Sep 7, 2022Physiology

Live-Cell Imaging in Human Colonic Monolayers Reveals Erk Waves Limit the Stem Cell Compartment to Maintain Epithelial Homeostasis

K. W. Pond, O. Alkhimenok, J. Chakrabarti, Y. Zavros, C. A. Thorne, A. L. Paek

The paper uses live-cell imaging in human colonic organoids to show Erk signaling waves maintain stem cell compartments and tissue homeostasis by restricting stem cell expansion.

bioRxiv · Feb 23, 2022Cell Biology

Toll Like Receptor 9 Pathway Mediates Schlafen+-MDSC Polarization During Helicobacter-Induced Gastric Metaplasias

L. L. Ding, J. L. Chakrabarti, S. Sheriff, Q. Li, H. N. Thi Hong, R. A. Sontz, Z. E. Mendoza, A. Schreibeis, M. A. Helmrath, Y. Zavros, J. L. Merchant

This study shows that TLR9 mediates SLFN+-MDSC polarization during Helicobacter-induced gastric metaplasia, with the TLR9 C allele linked to increased risk of neoplastic complications.

bioRxiv · Jan 25, 2022Cancer Biology

Gastric metabolomics analysis supports H. pyloris catabolism of organic and amino acids in both the corpus and antrum

D. Keilberg, N. Steele, S. Fan, C. Yang, Y. Zavros, K. M. Ottemann

This study compares metabolomics profiles in mouse gastric corpus and antrum organoids and tissue, revealing distinct metabolic differences and H. pylori nutrient utilization patterns.

bioRxiv · Jul 1, 2020 · PreprintMicrobiology