Author

K. O. Schink

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 5 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 6 Research Focus:cell signaling & trafficking· 4 Research Focus:cell type annotation· 3 Research Focus:development & morphogenesis· 2 Organism:human· 2 Assay:proteomics· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:differential expression· 1

Frequent Co-Authors

H. Stenmark· 5 shared C. Raiborg· 2 shared E. M. Wenzel· 2 shared K. W. Tan· 2 shared A. Bongiovanni· 1 shared A. Brech· 1 shared A. Poswiata· 1 shared B. Diederich· 1 shared

Activity by Year

2018-2022 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 15 mutual co-author links

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5 shared papersCell Biology

H. Stenmark

Mutual co-authors in cluster

Author profile →

6 papers

Recent·Most cited

ATPase activity of DFCP1 controls selective autophagy

V. Nähse, C. Raiborg, K. W. Tan, S. Mørk, M. L. Torgersen, E. M. Wenzel, M. Nager, V. T. Salo, T. Johansen, E. Ikonen, K. O. Schink, H. Stenmark

This study identifies DFCP1 as an ATPase essential for omegasome constriction and selective autophagy by facilitating autophagosome release.

bioRxiv · Feb 24, 2022Cell Biology

A phosphoinositide and RAB switch controls early macropinocytosis

H. Spangenberg, M. Sneeggen, M. Mateo Tortola, C. Valenzuela-Montenegro, Y.-Y. Chang, H. Stenmark, C. Raiborg, K. O. Schink

This study identifies a phosphoinositide and RAB switch that regulates macropinosome fate between endolysosomal maturation and a secretory route.

bioRxiv · Nov 3, 2021Cell Biology

JIP4 is recruited by the phosphoinositide-binding protein Phafin2 to promote recycling tubules on macropinosomes

K. W. Tan, V. Nähse, C. Campsteijn, A. Brech, K. O. Schink, H. Stenmark

This study identifies JIP4 and Phafin2 as components of a tubular recycling pathway from macropinosomes, showing JIP4 recruitment via Phafin2's PtdIns3P binding.

bioRxiv · Sep 29, 2020Cell Biology

Nanoscopy on the Chea(i)p

B. Diederich, O. I. Helle, P. Then, P. Carravilla, K. O. Schink, F. Hornung, S. Deinhardt-Emmer, C. Eggeling, B. S. Ahluwalia, R. Heintzmann

This paper presents a low-cost, 3D-printed super-resolution microscope using a cellphone for imaging and processing, achieving 100nm resolution and enabling live imaging of SARS-CoV-2 viroids.

bioRxiv · Sep 4, 2020 · PreprintMicrobiology

GAS6-AXL signaling triggers actin remodeling and macropinocytosis that drive cancer cell invasion

D. Zdzalik-Bielecka, A. Poswiata, K. Kozik, K. Jastrzebski, K. O. Schink, M. Brewinska-Olchowik, K. Piwocka, H. Stenmark, M. Miaczynska

This study identifies GAS6-AXL signaling as a driver of cancer cell invasion through actin remodeling and macropinocytosis in glioblastoma cells under glutamine-deprived conditions.

bioRxiv · Mar 15, 2020 · PreprintCell Biology

ESCRT-mediated lysosome repair precedes lysophagy and promotes cell survival

M. Radulovic, A. Bongiovanni, K. O. Schink, V. Nähse-Kumpf, E. M. Wenzel, F. Lafont, H. Stenmark

The paper shows ESCRT machinery repairs damaged lysosomes before lysophagy, promoting cell survival and aiding intracellular pathogens.

bioRxiv · May 3, 2018Cell Biology