Author

K. S. H. Beckham

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Assay:cryo-EM· 1 Research Focus:drug response / drug discovery· 1 Research Focus:protein structure prediction· 1

Frequent Co-Authors

M. Wilmanns· 2 shared A. Parret· 1 shared B. B. Aldridge· 1 shared C. Ritter· 1 shared E. Mullapudi· 1 shared F. P. Maurer· 1 shared F. Vasquez Sotomayor· 1 shared G. Chojnowski· 1 shared

Activity by Year

2020-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersMicrobiology

M. Wilmanns

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2 papers

Recent·Most cited

MicrobiologybioRxivJul 12, 2021

C25-modified rifamycin derivatives with improved activity against Mycobacterium abscessus

L. Paulowski, K. S. H. Beckham, M. D. Johansen…·F. P. Maurer

This study develops a C25-modified rifamycin derivative, 5j, which resists enzymatic inactivation by ArrMab and shows potent antimicrobial activity against M. abscessus in vitro and in macrophages.

DOI 10.1093/pnasnexus/pgac130

experimental assaydrug response / drug discovery

𝕏 PostBluesky

MicrobiologybioRxivNov 17, 2020

Structure of the mycobacterial ESX-5 Type VII Secretion System hexameric pore complex

K. S. H. Beckham, C. Ritter, G. Chojnowski…·M. Wilmanns

The paper presents a high-resolution cryo-EM structure of the ESX-5 Type VII secretion system hexameric pore complex, revealing its assembly and potential gating mechanisms.

DOI 10.1126/sciadv.abg9923

cryo-EMexperimental assay

𝕏 PostBluesky