Author

G. Chojnowski

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2 Biophysics· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Assay:cryo-EM· 2 Research Focus:protein structure prediction· 2 Approach:benchmark study· 1 Research Focus:benchmarking· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Organism:mouse· 1

Frequent Co-Authors

M. Wilmanns· 2 shared S. A. Mortensen· 2 shared A. Bochel· 1 shared A. Kryshtafovych· 1 shared A. L. Matveev· 1 shared A. P. Joseph· 1 shared A. Patwardhan· 1 shared A. Perez· 1 shared

Activity by Year

2020-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 18 mutual co-author links

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Curved chords = mutual co-authorship

2 shared papersBiophysics

M. Wilmanns

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Structure of the N-terminal didomain d1_d2 of the Thrombospondin type-1 domain-containing 7A

A. Bochel, S. A. Mortensen, L. Seifert, F. E. Hengel, C. M. Jeffries, G. Chojnowski, O. Kretz, T. B. Huber, N. M. Tomas, M. Wilmanns

This study determines the structure of the N-terminal didomain d1_d2 of THSD7A, revealing a non-canonical thrombospondin repeat fold with unique structural features contributing to its antigenicity.

bioRxiv · May 3, 2023 · PreprintBiophysics

Structural insights into tick-borne encephalitis virus neutralization and animal protection by a therapeutic antibody

I. K. Baykov, G. Chojnowski, P. Pachl, A. L. Matveev, N. A. Moor, L. A. Emelianova, P. M. Rezacova, V. S. Lamzin, N. V. Tikunova

This paper identifies the epitope and mechanism of a therapeutic antibody against TBEV, showing how it neutralizes the virus and prevents infection.

bioRxiv · Jul 28, 2021 · PreprintBiochemistry

Structure of the mycobacterial ESX-5 Type VII Secretion System hexameric pore complex

K. S. H. Beckham, C. Ritter, G. Chojnowski, E. Mullapudi, M. Rettel, M. M. Savitski, S. A. Mortensen, J. Kosinski, M. Wilmanns

The paper presents a high-resolution cryo-EM structure of the ESX-5 Type VII secretion system hexameric pore complex, revealing its assembly and potential gating mechanisms.

bioRxiv · Nov 17, 2020Microbiology

Outcomes of the 2019 EMDataResource model challenge: validation of cryo-EM models at near-atomic resolution

C. L. Lawson, A. Kryshtafovych, P. D. Adams, P. Afonine, M. L. Baker, B. A. Barad, P. Bond, T. Burnley, R. Cao, J. Cheng, G. Chojnowski, K. Cowtan, K. A. Dill, F. DiMaio, D. Farrell, , Wan

The paper evaluates cryo-EM model quality using benchmark maps, showing high accuracy and reproducibility across 13 teams and recommending multiple metrics for model assessment.

bioRxiv · Jun 12, 2020Biochemistry