Dynamic clustering of dynamin-amphiphysin rings regulates membrane constriction and fission coupled with GTP hydrolysis
T. Takeda, T. Kozai, H. Yang, D. Ishikuro, K. Seyama, Y. Kumagai, T. Abe, H. Yamada, T. Uchihashi, T. Ando, K. Takei
This study uses EM and HS-AFM to show dynamin-amphiphysin rings cluster during GTP hydrolysis, driving membrane constriction and fission through a novel clusterase mechanism.
bioRxiv · Aug 20, 2017Biophysics