Author

K. Silina

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Cancer Biology· 1 Immunology· 1 Pathology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Research Focus:cell type annotation· 2 Research Focus:cell-cell communication· 2 Approach:experimental assay· 2 Organism:human· 2 Organism:mouse· 2 Research Focus:clustering· 1 Approach:deep learning· 1 Research Focus:differential expression· 1

Frequent Co-Authors

M. van den Broek· 3 shared H. Moch· 2 shared V. Cecconi· 2 shared A. L. Calvanese· 1 shared B. Becher· 1 shared B. Ludewig· 1 shared B. Sobottka· 1 shared C. Schneider· 1 shared

Activity by Year

2020-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 26 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

3 shared papersImmunology

M. van den Broek

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Sustained innate interferon is an essential inducer of tertiary lymphoid structures

A. L. Calvanese, V. Cecconi, S. Staehli, D. Schnepf, P. Pereira, J. Gschwend, M. Heikenwaelder, C. Schneider, B. Ludewig, K. Silina, M. van den Broek

This study identifies sustained type I interferon signaling as essential for the development of functional tertiary lymphoid structures in the lungs during inflammation.

bioRxiv · Apr 30, 2024Immunology

Multi-resolution deep learning characterizestertiary lymphoid structures in solid tumors

M. van Rijthoven, S. Obahor, F. Pagliarulo, M. van den Broek, P. Schraml, H. Moch, J. van der Laak, F. Ciompi, K. Silina

This paper introduces HookNet-TLS, a deep learning model for automated TLS quantification in cancer pathology slides, achieving human-level performance and prognostic associations.

bioRxiv · Apr 3, 2023Pathology

CD39+PD-1+CD8+ T cells mediate metastatic dormancy in breast cancer

P. Tallon de Lara, H. Castanon, M. Vermeer, N. Nunez, K. Silina, B. Sobottka, J. Urdinez, V. Cecconi, F. Movahedian Attar, S. Hiltbrunner, I. Glarner, H. Moch, S. Tugues, B. Becher, M. van den Broek

This study identifies CD39+PD-1+CD8+ T cells as critical for metastatic dormancy in breast cancer, showing their role in suppressing tumor growth and their potential as a biomarker and immunotherapy target.

bioRxiv · Jun 2, 2020Cancer Biology