CD39+PD-1+CD8+ T cells mediate metastatic dormancy in breast cancer
P. Tallon de Lara, H. Castanon, M. Vermeer, N. Nunez, K. Silina, B. Sobottka, J. Urdinez, V. Cecconi, F. Movahedian Attar, S. Hiltbrunner, I. Glarner, H. Moch, S. Tugues, B. Becher, M. van den Broek
This study identifies CD39+PD-1+CD8+ T cells as critical for metastatic dormancy in breast cancer, showing their role in suppressing tumor growth and their potential as a biomarker and immunotherapy target.
bioRxiv · Jun 2, 2020Cancer Biology