Author

K. T. Dao

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 2 Approach:experimental assay· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:drug response / drug discovery· 1 Organism:human· 1 Research Focus:metabolism & bioenergetics· 1

Frequent Co-Authors

A. Mercer· 2 shared D. Biswas· 2 shared L. Duffley· 2 shared T. Pulinilkunnil· 2 shared A. M. Cowie· 1 shared L. Slade· 1 shared N. Mueller· 1 shared P. C. Kienesberger· 1 shared

Activity by Year

2020-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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2 shared papersCancer Biology

A. Mercer

Mutual co-authors in cluster

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2 papers

Recent·Most cited

Inhibiting BCKDK in triple-negative breast cancer suppress protein translation, impair mitochondrial function, and potentiate doxorubicin cytotoxicity

D. Biswas, L. Slade, L. Duffley, N. Mueller, K. T. Dao, A. Mercer, S. Pakkiriswami, Y. El-Hiani, P. Kieneseberger, T. Pulinilkunnil

This study shows that inhibiting BCKDK in TNBC cells reduces protein translation, impairs mitochondrial function, and enhances doxorubicin-induced cell death.

bioRxiv · May 18, 2021Cancer Biology

Silencing branched-chain ketoacid dehydrogenase or treatment with branched-chain ketoacids ex vivo inhibits muscle insulin signaling

D. Biswas, K. T. Dao, A. Mercer, A. M. Cowie, L. Duffley, Y. El Hiani, P. C. Kienesberger, T. Pulinilkunnil

This study shows that BCKAs inhibit muscle insulin signaling and that reducing BCKA levels improves insulin signaling and mitochondrial respiration in skeletal muscle cells.

bioRxiv · Feb 21, 2020 · PreprintCell Biology