Author

K. T. Simon

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Biophysics· 1

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Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Organism:chicken / avian· 1 Research Focus:chromatin & epigenetic regulation· 1 Approach:experimental assay· 1 Organism:human· 1 Assay:imaging· 1 Approach:statistical model· 1

Frequent Co-Authors

C. R. Pfeifer· 1 shared D. E. Discher· 1 shared E. G. Ricci-De Lucca· 1 shared L. J. Dooling· 1 shared L. L. Vasquez· 1 shared M. P. Tobin· 1 shared M. Vashisth· 1 shared S. Cho· 1 shared

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2021-2021 · peak 1/yr

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1 shared paperBiophysics

C. R. Pfeifer

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1 paper

Recent·Most cited

Gaussian curvature dilutes the nuclear lamina, favoring nuclear rupture, especially at high strain rate

C. R. Pfeifer, M. P. Tobin, S. Cho, M. Vashisth, L. J. Dooling, L. L. Vasquez, E. G. Ricci-De Lucca, K. T. Simon, D. E. Discher

The paper shows that high nuclear curvature causes lamin-B dilution and rupture, with lamin-A also contributing under high strain rates, suggesting a viscoplastic response to mechanical stress.

bioRxiv · Oct 13, 2021Biophysics