Biochemical Adaptations Of The Retina And Retinal Pigment Epithelium Support A Metabolic Ecosystem In The Vertebrate Eye
M. A. Kanow, M. M. Giarmarco, C. Jankowski, K. Tsantilas, A. L. Engel, J. Du, J. D. Linton, C. C. Farnsworth, S. R. Sloat, K. J. Lindsay, E. D. Parker, S. E. Brockerhoff, M. Sadilek, J. R. Chao, J. B. Hurley
The paper presents a model of retinal metabolism showing glucose is converted to lactate by photoreceptors and used by retinal pigment epithelium and Muller glial cells, with implications for retinal disease and therapy.
bioRxiv · May 29, 2017Biochemistry