Author

E. D. Parker

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 3 Cell Biology· 2 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Research Focus:development & morphogenesis· 3 Research Focus:metabolism & bioenergetics· 3 Research Focus:cell signaling & trafficking· 2 Research Focus:cell type annotation· 2 Organism:human· 2 Organism:zebrafish· 2 Research Focus:differential expression· 1

Frequent Co-Authors

S. E. Brockerhoff· 3 shared D. C. Brock· 2 shared J. B. Hurley· 2 shared J. Du· 2 shared K. A. Tsantilas· 2 shared M. M. Giarmarco· 2 shared W. Ge· 2 shared W. M. Cleghorn· 2 shared

Activity by Year

2017-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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3 shared papersCell Biology

S. E. Brockerhoff

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Author profile →

6 papers

Recent·Most cited

Disruption of myelin structure and oligodendrocyte maturation in a pigtail macaque model of congenital Zika infection

J. Tisoncik-Go, C. Stokes, L. Whitmore, D. J. Newhouse, K. Voss, A. Gustin, C.-J. Song, E. Smith, J. Stencel-Baerenwald, E. D. Parker, J. M. Snyder, D. Shaw, L. Rajagopal, R. P. Kapur, K. A. Waldorf, M. Gale

This study investigates the effects of prenatal Zika virus exposure on fetal myelin structure and oligodendrocyte maturation in pigtail macaques, finding disruptions in myelin formation and gene expression related to oligodendrocyte development.

bioRxiv · Oct 11, 2023Immunology

Mag-Net: Rapid enrichment of membrane-bound particles enables high coverage quantitative analysis of the plasma proteome

C. C. Wu, K. A. Tsantilas, J. Park, D. L. Plubell, J. A. Sanders, P. Naicker, I. Govender, S. Buthelezi, S. Stoychev, J. Jordaan, G. E. Merrihew, E. Huang, E. D. Parker, M. Riffle, A. N. Hoofnagle, , M. J. MacCoss

Mag-Net enriches membrane-bound particles from plasma to identify disease-specific proteins, discovering 204 proteins differentiating Alzheimer's disease dementia from controls.

bioRxiv · Jun 10, 2023 · PreprintBiochemistry

Isocitrate dehydrogenase 3b is required for spermiogenesis but dispensable for retinal degeneration

J. Du, S. Zhu, J. Huang, R. Xu, Y. Wang, Y. Wan, R. McNeel, E. D. Parker, D. Kolson, M. Yam, B. Webb, C. Zhao

This study shows IDH3B is essential for spermiogenesis but not retinal health, as Idh3b-knockout mice are infertile but have normal vision.

bioRxiv · Feb 9, 2022 · PreprintBiochemistry

Daily mitochondrial dynamics in cone photoreceptors

M. M. Giarmarco, D. C. Brock, B. M. Robbings, W. M. Cleghorn, K. A. Tsantilas, K. C. Kuch, W. Ge, K. M. Rutter, E. D. Parker, S. E. Brockerhoff

The paper examines daily mitochondrial dynamics in zebrafish cone photoreceptors, finding increased mitochondrial biogenesis at night and structural changes during the day.

bioRxiv · Apr 10, 2020Cell Biology

Mitochondrial Ca2+ influences photoresponse recovery, metabolism, and mitochondrial localization in cone photoreceptors

R. A. Hutto, C. M. Bisbach, F. Abbas, D. C. Brock, W. M. Cleghorn, E. D. Parker, B. H. Bauer, W. Ge, F. Vinberg, J. B. Hurley, S. E. Brockerhoff

This study shows that low mitochondrial Ca2+ uptake in zebrafish cone photoreceptors affects photoresponse recovery, metabolism, and mitochondrial localization, with increased MCU expression altering these processes.

bioRxiv · Jan 3, 2019Cell Biology

Biochemical Adaptations Of The Retina And Retinal Pigment Epithelium Support A Metabolic Ecosystem In The Vertebrate Eye

M. A. Kanow, M. M. Giarmarco, C. Jankowski, K. Tsantilas, A. L. Engel, J. Du, J. D. Linton, C. C. Farnsworth, S. R. Sloat, K. J. Lindsay, E. D. Parker, S. E. Brockerhoff, M. Sadilek, J. R. Chao, J. B. Hurley

The paper presents a model of retinal metabolism showing glucose is converted to lactate by photoreceptors and used by retinal pigment epithelium and Muller glial cells, with implications for retinal disease and therapy.

bioRxiv · May 29, 2017Biochemistry