Adversary of DNA integrity: a long non-coding RNA stimulates driver oncogenic chromosomal rearrangement in human thyroid cells
D. E. Demin, M. M. Murashko, A. N. Uvarova, E. M. Stasevich, E. Y. Shyrokova, G. E. Gorlachev, K. V. Korneev, A. S. Ustiugova, E. A. Tkachenko, V. V. Kostenko, K. A. Tatosyan, S. A. Sheetikov, P. V. Spirin, D. V. Kuprash, A. M. Schwartz
This study identifies lncRNA CASTL1 as a stimulator of the CCDC6-RET chromosomal rearrangement in thyroid cells exposed to DNA damage.
bioRxiv · Mar 25, 2022Cancer Biology