K. V. Venkatesh

Ultrasensitive Regulation in the Tryptophan System in Escherichia coli Provides Effective Noise Mitigation

This study analyzes the tryptophan system in E. coli to show how multiple feedback loops enable rapid response and noise mitigation.

Mutant strains of Escherichia coli lacking global regulators, arcA and fis, demonstrate better growth fitness by pathway reprogramming under acetate metabolism

This study shows that E. coli mutants lacking arcA and fis grow faster under acetate metabolism due to metabolic reprogramming, with increased TCA cycle flux and reduced gluconeogenesis.

Ligand Sensing Enhances Bacterial Flagellar Motor Output via Stator Recruitment

This study shows that bacteria can modulate flagellar motor speed through ligand sensing, not just altering rotation bias, with metabolisable ligands causing prolonged speed increases.

Effect of ligand sensing on flagellar bundle formation in bacteria

This study shows that ligand sensing in E. coli increases flagellar bundle tightness and swimming speed by enhancing motor torque and CCW bias, independent of metabolism.

\"Viscotaxis\" - Directed Migration of Mesenchymal Stem Cells in Response to Loss Modulus Gradient

This study shows that human mesenchymal stem cells migrate from high to low loss modulus in response to viscous gradients, termed 'viscotaxis', and identifies cellular traction as the mechanism.