Author

K. Vanhoorelbeke

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 3 Organism:mouse· 2 Research Focus:drug response / drug discovery· 1 Organism:human· 1 Assay:proteomics· 1

Frequent Co-Authors

H. J. Thibaut· 2 shared J. Lammertyn· 2 shared J. Neyts· 2 shared K. Ven· 2 shared L. Ampofo· 2 shared M. Imbrechts· 2 shared N. Callewaert· 2 shared N. Geukens· 2 shared

Activity by Year

2020-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersImmunology

H. J. Thibaut

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Author profile →

3 papers

Recent·Most cited

Anti-SARS-CoV-2 human antibodies retaining neutralizing activity against SARS-CoV-2 B.1.1.529 (omicron)

M. Imbrechts, W. Kerstens, M. Rasulova, T. Vercruysse, W. Maes, L. Ampofo, K. Ven, J. Lammertyn, K. Vanhoorelbeke, N. Callewaert, J. Neyts, K. Dallmeier, P. Declerck, H. J. Thibaut, N. Geukens

The paper evaluates a panel of anti-SARS-CoV-2 monoclonal antibodies for neutralizing activity against SARS-CoV-2 delta and omicron variants, finding three mAbs retain activity, with mAb 3B8 showing potent neutralization against both.

bioRxiv · Dec 21, 2021 · PreprintImmunology

Potent neutralizing anti-SARS-CoV-2 human antibodies cure infection with SARS-CoV-2 variants in hamster model

M. Imbrechts, W. Maes, L. Ampofo, N. Van den Berghe, B. Calcoen, D. Van Looveren, S. Noppen, K. Hollevoet, T. Vercruysse, X. Zhang, R. Abdelnabi, C. S.-Y. Foo, H. J. Thibaut, D. Jochmans, K. Ven, , N. Geukens

The paper identifies potent anti-SARS-CoV-2 mAbs that cure infection in hamsters and demonstrates gene-based delivery for in vivo protection against variants.

bioRxiv · Nov 25, 2021Immunology

The GPIbα intracellular tail - role in transducing VWF- and Collagen/GPVI-mediated signaling

A. Constantinescu-Bercu, Y. A. Wang, K. Woollard, P. Mangin, K. Vanhoorelbeke, J. T. Crawley, I. I. Salles-Crawley

This study shows that the GPIb intracellular tail is essential for both VWF- and collagen-GPVI-mediated signaling in platelets, revealing crosstalk between these pathways.

bioRxiv · Dec 16, 2020Cell Biology